Preliminary data suggest metformin is associated with diseases, and a small study showed it improved outcomes in 15 older adults compared to placebo.

“it's pectin with metformin studies so our reviewers we're saying you know okay all the data on the biology that you showed was from rodents and we don't know that the biology is real to humans okay although of course the preliminary data in humans are much better than in rodents right the association with diseases so we had a clinical studies a small clinical study which we took 15 people that are 75 years old and we gave some of them at forming for six weeks and other placebos and then we crossed over”