Metformin and the TAME trial
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Metformin and the TAME trial
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
and you're gonna randomized one to one or two to one one to one or two to one one to one and the placebo versus what dose of metformin two grams 1500
one gram twice a day 1500 milligram of extended release they'll get three tablets every morning or every night whatever they choose 300 500 milligram extended release peels
for metformin what needs to be considered is that tame will answer some
the tank study will provide maybe later but will provide some more evidence
by the way in tame study we're going to follow those those patients that were sensitive to metformin and see if there's something unique about them that's one of the things we hope to do
there is a study that is eventually getting funded in fact it might I mean technically I guess it is funded I don't know if it's began enrollment yet called the tame study and the tame study is going to attempt to answer this question in humans by studying disease onset in susceptible but otherwise helpful healthy individuals
there is a study that is eventually getting funded in fact it might I mean technically I guess it is funded I don't know if it's began enrollment yet called the tame study and the tame study is going to attempt to answer this question in humans by studying disease onset in susceptible but otherwise helpful healthy individuals
tame is in a very preliminary State there's now enough money to get it started previously so it has not it has not enrolled anything yet it's enrolling right now