right so the way we organize the study and this is also in negotiation with the nih we will have auxiliary ancillary studies that will be reviewed sometimes you need only 250 people so you it can be in one center we have 14 centers and part of the examples we gave is actually immunity that was the example we had it was against the flu but of course now we're talking about if we start before immunization will immunize for influenza the first year and see the response and then for covet 19 the next year and see the response