The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
if you take somebody who is already maximizing the benefits of exercise nutrition sleep these things that I think the more we look at them the more powerful they are it's one thing to say the addition of metformin offers minimal benefit or incremental benefit
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
it almost seems like it falls potentially into the metformin trap which is the metformin data in metabolically unhealthy people it's pretty hard to argue and metformin is beneficial paradoxically the people who are most obsessed with this stuff are already doing so many of the other quote unquote good lifestyle things that it you wonder is it possible that you're already doing such a good job of all the other things you manage with respect to your health the resveratrol is neutral
there are a couple of papers that have come out kind of recently that have suggested hey maybe metformin in the metabolically healthy person and or