The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
and and anti-kinase is is naturally sensing the levels of amp in the cell right and amp is what you get when you don't have a lot of atp which is the chemical energy store like the the the battery pack uh and so uh mitochondria constantly turning amp um and adp into atp
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One of the important signals is something called a MP kinase the change in the ATP to adp ratio that's known to be one of the activators of this particular transcriptional program that induces mitochondrial biogenesis
I think when we talk about exercise I think EMP activation is generally regarded as one of the important signals for mitochondrial biogenesis but I don't think it is sufficient it's not sufficient