Paul Saladino· MD
superoxide and or hydrogen peroxide are the stop signal saying we don't need any more calories either being put into the electron transport chain or because hydrogen peroxide travels some distance away from the mitochondria or into the cell so this is your stop button that and it's not all or nothing you don't suddenly stop accepting calories completely it's it's a graduated response your atp demand is being met meta met so you want less and less and less calories more and more superoxide and hydrogen peroxide should shut down the ingress of calories into that given cell that's how the system is is controlled