Skeletal muscle cells can use ketone bodies like acetoacetate to enter the Krebs cycle.

“you can acetoacetate can break down and provide acetyl co a before the Krebs like so what we're finding is that the krebs cycle is not the simple cycle that we thought it was especially as it relates to cancer cells so it's almost like we can't even look at the biochemistry book and kind of pinpoint different pathways with substrate level phosphorylation there are a number of different pathways like the malate aspartate shuttle that are associated with cancer cells”