NR-supplemented mothers in mice produced more milk, leading to better weight management and potentially higher levels of bioactives in their offspring.

“Supplementing nursing mouse mothers with nicotinamide riboside promotes maternal weight loss, boosts milk production/quality, and leads to offspring that have better motor coordination, better learning/memory, less anxiety and more resilient to stress.”

“Supplementing nursing mouse mothers with nicotinamide riboside promotes maternal weight loss, boosts milk production/quality, and leads to offspring that have better motor coordination, better learning/memory, less anxiety and more resilient to stress.”

“Supplementing nursing mouse mothers with nicotinamide riboside promotes maternal weight loss, boosts milk production/quality, and leads to offspring that have better motor coordination, better learning/memory, less anxiety and more resilient to stress.”

“And what we found is that the offspring of supplemented mothers had better lean mass um at the time of weaning that they were able to maintain for their whole lives. They had um faster uh mechanical physical development. So their performance on like a balance beam type thing was better if the mom was supplemented. Um they had lower fear and anxiety to the degree to which you can test such things in in mice. Um so they did better on a Morris water maze and they even had better adult hippocample neurogenesis if the mom had been supplemented.”

“So it turns out that the NR supplemented new moms also had better weight management, right? And it was simply calorie transfer. They produced more milk.”