Paul Saladino· MD
NR and NMN may increase NAD+ but also will also increase NAM leading to consumption of methyl groups from SAMe… not good!
We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
NR and NMN may increase NAD+ but also will also increase NAM leading to consumption of methyl groups from SAMe… not good!
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
the problem with nad from nmn or nr is that it increases nam nicotinamide leading to depletion of methyl donors from sam e