The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
the MTHFR shuts down in the fed state if you ate protein the enzyme that uses we say protein do you mean specifically methionine well there's no finding a net in every protein there's more methionine in eggs there's more methionine in meat compared to plant foods but there's enough methionine that if you just eat a meal that has a reasonable amount of protein you're going in this direction
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
so you totally shut down and THF are you totally shut down the enzyme that uses choline so you're not recycling it anymore and then you flip on this other enzyme that's not usually active that gets rid of the homocysteine by just breaking it down and then on top of that you want to get rid of the extra methyl groups and you turn on this other enzyme that is going to use the amino acid glycine as a buffer and then that glycine is going to if it can hold on to the methyl group for later use but if you methylate too much of that glycine you end up peeing it out