Paul Saladino· MD
we went through all the mechanistic data or at least scratched the surface on different mechanisms heme iron not a problem because in vitro studies use doses that are massive or animal models use calcium deficient fat models and high doses and nitroso compounds not the same ones formed in humans from eating meat as have been shown to form DNA adducts or be problematic at the DNA level pchs polycyclic aromatic hydrocarbons or heterocyclic amines probably not an issue for humans unless you're eating exclusively burned charred meat without anything else