Rhonda Patrick· PhD
In a controlled study, mice given high PFAS exposure had significantly lower serum levels of multiple PFAS compounds (including PFHpA, PFOA, and PFOS) when fed β-glucan over 6 weeks.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
In a controlled study, mice given high PFAS exposure had significantly lower serum levels of multiple PFAS compounds (including PFHpA, PFOA, and PFOS) when fed β-glucan over 6 weeks.
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In humans, a drug that mimics the effects of β-glucan by binding to forever chemicals in the gut reduced serum PFAS levels by 60% in adults living in a hotspot for forever chemical exposure.
The mechanism appears to be enhanced PFAS excretion and elimination from the body.