Paul Saladino· MD
I think what's happening there is basically the ketogenic diet is causing oxidative stress that's increasing the demand for glutathione and the hippocampus and there's a reaction to that that makes more glutathione
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
I think what's happening there is basically the ketogenic diet is causing oxidative stress that's increasing the demand for glutathione and the hippocampus and there's a reaction to that that makes more glutathione
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
I would absolutely hedge my bets on ketogenic diets lowering whole body glutathione synthesis markers but I don't believe anyone's studied a clearly in humans before