Paul Saladino· MD
the paper is in cell which is a very highly regarded journal title is a dietary fiber deprived gut microbiota degrades the colonic mucous barrier and enhances pathogen susceptibility which sounds like oh [ __ ] like we need it right but if you actually look at the paper the paper is done in animals so this is a mouse study and what they did was they began with Noto biotic mice which are mice that are raised with a germ-free gut and they introduced into the gut of these nota biotic mice a14 bacteria containing human-like microbiome so the 14th x here is human like 14 specie the bacteria which were supposed to be a human-like microbiome that's like saying that water that blood is just water and iron right right right so they created this human-like microbiome in a mouse and of composed of 14 species which were all fairly predisposed to eat carbohydrates so it was a carbohydrate loving series of bacteria will read that I read the paper they can see which ones they actually use it's here on the paper I can tell you the names of the bacteria you know they use back to Roy to tease Oh baddest back to Roy to tease uniform us etcetera etc blah blah blah you know you bacterium rekt all a rose Berea and testin Alice they didn't use Ackerman Co they use an e coli species and I use Clostridium some bio some but they they admit that this is a fiber liking set of bacteria so they they use a synthetic got synthetic human gut microbiome in no de biotic mice and then what do they do for the intervention they give some mice high fiber diets and that some mice low fiber diets and they compare to see what happens to be mice gut and the mice microbiome well but they don't compare health outcomes they there were no differences in health outcomes so-so histopathology and body weight measurements over time of mice from the groups with reduced mucus thickness did not reveal changes compared to the mice consuming the full fiber diet so what they're saying is that there was a small decrease in the mucous layer of the guts of these mice that were fed very low fiber diets but there was no change in the histopathology which could indicate any real path in any real pathogenesis so they say collectively the data transcribed above indicate that fiber restricted colonized mice experience some erosion of the mucus barrier and some altered intestinal response is albeit without overt signs of disease so there was no evidence that there was any disease and there was no histopathologic change in the any of them you cells below the gut below the lining of the mucus so basically this is the study that Steven Gundry and