Continuous activation of mTOR through frequent small meals, especially those high in carbohydrates, is detrimental, whereas targeted activation of mTOR in muscle via specific meals is beneficial for muscle protein synthesis.

“what we want to do is use specific meals with the right amount of insulin to activate muscle Centric uh mtor mtor is in every tissue and what you don't want to do is continuously activate it in liver or some other tissue and so that's where the confusion gets into it is people ignore the fact that insulin is just a bigest trigger in other tissues where Lucine is a very unique trigger in muscle”