Papaya seeds contain toxins and are not recommended for consumption unless one has parasites.

“don't eat papaya seeds guys don't even don't even put the papaya seeds in your mouth holy that's crazy it reminds me of when i go back to austin and i try and eat a papaya because here in costa rica we have the best papayas i cut it open they're full of these like plump seeds and and no i don't eat the seeds guys i know in like hippy-dippy circles i say the seeds are anti-parasitic which may be the case because the seeds have a bunch of toxins in them but i don't have any parasites i don't need to eat papaya seeds they're not good to eat if i don't have parasites”