Paul Saladino· MD
so if I'm eating a lot of fat then my body feels less of a need to mobilize existing fat that's on my body and therefore it makes less of its counterpart to chylomicrons which are the vldls
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
so if I'm eating a lot of fat then my body feels less of a need to mobilize existing fat that's on my body and therefore it makes less of its counterpart to chylomicrons which are the vldls
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if I'm not eating a lot of that what happens while my body needs to activate more lipolysis you know my my insulin goes down my glucagon goes up more of those free fatty acids then are making their way to the liver more the LDL is back and supply to compensate for the lack of chylomicrons and therefore the resupply the constant resupply of those triglycerides back to my tissues me there's more left over succeeding LDLs and therefore more ldl-cholesterol