Paul Saladino· MD
if you have full glycogen stores how is the physiology different between high carb and low carb the only question is can you do glycolysis clearly if you're using the gleich you have the enzymes for glycolysis even though pyruvate dehydrogenase may be down regulated you're not gonna push it into acetic away in the Krebs cycle you are still doing glycolysis and using that fuel you're burning that glycogen and anaerobic metabolism you can still do that even if pdh is down regulated