Humans are more sensitive to sugar than most animals due to the uricase mutation.

“and so this mutation probably occurred at a critical time that provided survival for those apes in europe to be able to get out of there and make it back to these other regions but it was now equipped with this mutation that made it sensitive to sugar and so humans are much more sensitive to sugar than most animals and it's because of this mutation and in fact we actually resurrected the extinct ura case and proved this using the extinct ura case that showing that when you put it into human cells that it suddenly made us less sensitive to fructose”