A defect in delta-6 and delta-5 desaturase activity leads to inadequate formation of essential fatty acids and other important compounds.

“a defect in the activity of d6 and d5 decreases the formation of gla dgla arachidonic acid we talked about that epa dha and ala from linoleic acid this in turn leads to inadequate formation of prostaglandins prostacyclin like toxins resolvents neuroprotectants nitric oxide nitro lipids that have anti-inflammatory and anti-platelet effects”