The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
so I'm not telling you that their homocysteine is gonna go down when you put the choline in maybe it will there's Colleen's a methyl donor but what I'm telling you is that the data indicate that those people have a higher choline requirement and the way that you address that is by consuming enough choline
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900 at 1200 milligrams of choline will do two things one it will minimize markers of oxidative DNA damage and I'm not even sure if that mechanism is and the second thing that it does is it just you know it brings choline utilization markers back down to what you would find in someone who didn't have them th if our polymorphism
people with low MTHFR activity are doubling the amount of choline that they blow through and they have problems that are a result of not having enough choline that have nothing to do with homocysteine whatsoever that need to be fixed by putting more choline into the system
what I do know there's data on is showing that 900 at 1200 milligrams of choline will do two things one it will minimize markers of oxidative DNA damage
those people have a higher choline requirement