Paul Saladino· MD
And a recent study came out with sucralose showing that it increases blood flow to the hypothalamus. So it's it's changing the way your brain reacts to food in a way that it's probably making you hungrier.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
And a recent study came out with sucralose showing that it increases blood flow to the hypothalamus. So it's it's changing the way your brain reacts to food in a way that it's probably making you hungrier.
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Drinking beverages sweetened with the zero-calorie sweetener sucralose may significantly alter brain mechanisms involved in hunger regulation, according to a new brain imaging study. Acute consumption of sucralose increased hypothalamic blood flow by 7.9% compared to sugar-sweetened drinks (sucrose) and by 7.8% compared to water.
Increased hypothalamic blood flow is a neural marker typically associated with greater hunger, and indeed, hunger ratings were significantly higher after consuming sucralose.