Endurance training in mice induces autophagy, mediating anti-obesity and anti-diabetic effects dependent on autophagy induction.

“It is known that endurance training is particularly efficient in mice to induce autophagy and that it mediates anti-obesity and anti-diabetic effects that are depending, in a way, on autophagy induction, because genetic modifications of the process that leads to autophagy induction, it's inhibition, specifically by exercise, can prevent these anti-diabetic effects.”