Surgical removal of visceral fat depots in rats after puberty, even with ad libitum feeding, led to significantly longer lifespan (20% increase) compared to sham surgery controls, though not as much as caloric restriction.

“I took a bunch of Reds 150 actually and all of them underwent surgery after puberty in some of them I removed their visceral fat teapots by surgery and in the other it was a sham procedure just moved it but didn't remove it and we had three groups in the experiment one was ad libitum feeding the second was caloric restriction this is the control they would leave 40% better and the third group was ad libitum feeding of the rats that their visceral fat was removed and I said you know without the visceral fat even with nutrients they live longer and they actually lived significantly longer than they'd libitum by 20%”