Adversarial lifestyle choices can negatively affect nuclear transcription factors that regulate apoB particle clearance.

“so we could probably every adversarial thing you've been told in your life not to do gain weight don't eat this don't eat that are all affecting these nuclear transcription factors that are going to regulate clearance of these aobb particles and it is interesting that um that that on average more of the things that we do that are quote unquote less healthy he whether it be gain weight uh eat a certain way tends to result in decreased hepatic clearance”