The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
it seems like the only thing we know is it's not too low an amount of circulating leptin as evidenced by two things one the high circulating levels of leptin and the fact i think more importantly that when you give exogenous leptin it doesn't improve the condition suggesting that that's not the defect
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
yes i mean you can give high levels of leptin and it will cause weight loss but it doesn't do much