Women's evolutionary subcutaneous fat may mask insulin resistance before menopause but contributes to rapid weight gain after menopause.

“if we think about women's sort of procreation purpose in terms of being able to store fat enough having fat stores basically for lactation I think there is sort of a larger amount of subcutaneous safety belt for women and the issue is you're right after menopause I think that the big problem is before menopause we're not seeing the manifestations with instant resistance but after menopause all of a sudden it catches up right away”