Attempts at weight loss through calorie restriction and exercise often result in temporary weight loss followed by regaining the weight and more within a year.

“You tried eat less, move more. You were trying calorie restriction, exercising. Yeah. And it didn't work for you. Yeah. You know, I would have the brief success like lots of people, right? I remember for instance the chief my chief uh year, so the last year of my general surgery training and I said, I got to lose weight, right? I got to get under control. Uh this was right when uh the Palm Pilot had come out if you remember, right? One of the first sort of, you know, smartphonesish type devices. Yeah. And so, you know, I was able to like download a program, tracked everything I ate, you know, uh we had a gym right attached to the hospital, so between cases, I'd be going to work out, you know, really did it as best as you could do it. And yeah, I lost, you know, probably 40, 50 pounds that year. Um but within a year I had gained it all back and more.