Peter Attia· MD
neuropeptide Y actually changes what would be a lipolytic stimulus to a lipo genic stimulus
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neuropeptide Y actually changes what would be a lipolytic stimulus to a lipo genic stimulus
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the sympathetic nervous system normally which is lipolytic at least acutely becomes lipo Jenna chronically and the reason is because of the co factor that's released with the norepinephrine called neuropeptide Y neuropeptide Y actually changes what would be a lipolytic stimulus to a lipo genic stimulus so chronic over stimulation of the sympathetic nervous system leads to visceral fat accumulation
acutely nor epi will cause lipolysis through the beta3 adrenergic receptor at the level of the adipocyte but it causes lipogenesis when there are peptide Y's available