Peter Attia· MD
so you know both DHA and Pa are important in my mind for the brain as well I mean there's a variety of studies that have looked at even depression and like you can you can induce depressive symptoms in a person by injecting them with what's called lipopolysaccharide which is a component of the outer cell membrane of gram-negative bacteria we have millions of those in our gut in fact there's about one gram of lipopolysaccharide or LPS for short it's also referred to as endotoxin there's about one gram of that in our gut well you can inject people with a low dose of that something that actually would be somewhat you know I would say equivalent to someone with intestinal permeability and it can cause depressive symptoms in people compared to those given a placebo and you can blunt that depressive symptom effect with EPA probably because of the inflammatory the blunting of the inflammatory response