Rhonda Patrick· PhD
He had shown in animals, if you take animals and give them a human ApoE 3, 4, 2, and then feed them DHA orally, there was a transport defect in DHA across the blood-brain barrier. And so I kind of review this work on a variety of other papers as well, you know, where there's a couple of major mechanisms by which DHA is transported across the brain. Are you familiar with some of those? One is the through a free fatty acid and the other one's through an actual transporter called the Mfsd2a transporter, which is actually in a phospholipid form, DHA is in a phospholipid form. And so, it appears that there may be different ways, you know, that DHA gets across the brain, and one of the ways is potentially not working quite as well in ApoE4 individuals, at least that's my writing theory.