An EPA-only drug was approved in Japan in the late 1980s and used successfully in the 2007 JELIS trial.

“in the late 80s a EPA only drug was approved in Japan called eepa dil which is essentially that it's exactly the same thing as vas sebum in the Japanese back in the 1980s believe that it was EPA that was the active agent in fish oils so a drug company called Machida developed an EPA drug and they got it approved and they've been using that EPA drug for years and years and the jelous trial which was done published in 2007 which was a Japanese Omega 3 trial used this product called epidemic olive as SEPA and it was successful”