Exogenous ketones may influence the liver by decreasing gluconeogenesis and glycogenolysis, and enhancing insulin sensitivity for greater glucose disposal.

“I think consuming exogenous ketones uh influences the liver in ways that we don't understand. So one of uh I are the next big project that I want to do is liver metabolomics uh giving exogous ketones because the liver is the master regulator of metabolism especially in the context of everything really everything that we study. So what I think is happening is that it's decreasing gluconioenesis it's decre decreasing glycogenolyis and also simultaneously >> enhancing insulin sensitivity for greater glucose disposal.”