Molecular hydrogen's direct reaction with hydroxyl radicals is likely not a significant antioxidant mechanism due to the hydroxyl radical's high reactivity.

“But the biggest way it's targeted is actually is actually through the NRF2. That's one way. And through prevention because just to put this in in in perspective, although we're talking about hydrogen gas as this antioxidant radical scavenger to like react with hydroxy radical, it's it's probably not very significant. And that's because of the second order reaction rate constants. The hydroxal radical as I said is already reacting with whatever is right there. So when you look at the concentration of hydrogen molecule, the hydrogen molecule is you know billions of miles away from the where the O radical is. So it's unlikely for the O radical to like somehow travel over there react with that and form water.”