Peter Attia· MD
Neither LDL nor PCSK9i are capable of crossing into the CNS, which, even by late fetal development, begins to produce and recycle more than enough cholesterol to serve its own needs.
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Neither LDL nor PCSK9i are capable of crossing into the CNS, which, even by late fetal development, begins to produce and recycle more than enough cholesterol to serve its own needs.
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.