Peter Attia· MD
so the the way pcsk9 works is that it's a regulator of the ldl receptor
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
so the the way pcsk9 works is that it's a regulator of the ldl receptor
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
pcsk9 can bind to the ldl receptor that can happen inside the cell and when that happens the ldl receptor gets degraded in the lysosome that can also happen extracellularly