Inborn errors of metabolism like PKU may be treatable with gene therapy due to liver expression of relevant genes.

“many inborn errors of metabolism so things that are conditions like fenel Keon Nua but other things that have to do with the way the body digest processes metabolize Foods uh are some would say easier targets for gene therapy and we can go into more or less detail about this but in part many of these genes are expressed in the liver so the liver is kind of the if you want to think about it the metabolic brain of the body or the metabolic Clearing House the brain or rather the liver is a relatively easy place to Target in terms of gene therapy”