The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
what we also see is that in people who get mr inhibitors their innate antiviral gene expression is enhanced when they get a viral infection so what this suggests is early on like as post-exposure prophylaxis or pro in a prevention mode the rapalogs or the mtor inhibitors may have benefit by boosting the body's response that is defective as we get older to the virus so we can clear it better so that we don't go on to get severe symptoms from the virus
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
and in studies where we've looked at laboratory confirmed respiratory tract infections in our phase tube study we looked at 17 different viruses that caused respiratory tract infections in older people and four of them were the common coronaviruses and what we saw was that mtor inhibitors upregulated anterior gene expression and reduced the incidence and severity of coronavirus infections
what we've shown is that with mtor inhibitors you can enhance that interferon production in interferon induced gene expression and so the innate immune function enhancing that may be one of the reasons that the adaptive immune system is working better when you get vaccinated