Peter Attia· MD
for certain conditions where these are recessive conditions with loss of function you have to add back the missing enzyme or protein but you probably don't have to get to 100% And just for some of your listeners will be astute um you had alluded to carriers for these conditions recessive individuals who have one copy of the gene that's working just fine but one copy of the gene that's not they tend to be fine that was the point essentially of what you were saying do carriers have any advantage or disadvantage and and basically they're they're indistinguishable is what I would say which means for us in terms of a gene therapy or Gene addition or Gene replacement strategy you don't have to be perfect you have to get some in there you have to get enough in there but you don't have to get 100%