Cannabinoids do not cause fatal cardiorespiratory depression because CB1 receptors are not located in the brain's respiratory centers.

“the receptors those docking stations there are no cb1 receptors or very few in the cardio respiratory centers of our brain different than the opioid receptors the immune receptors where you overdose because that docking station gets activated by heroin or percocet or oxycontin and you slow down your respirations and you stop breathing and your heart slows down in your heart starts beating and you die that doesn't happen with cannabinoids because those receptors don't exist in those areas of the brain where that would happen”