Oral LHRH antagonists offer a shorter half-life compared to LHRH agonists, allowing for rapid testosterone recovery and are preferred for patients receiving short-course ADT with radiation.

“so the good news for men who are getting ADT short course is that there are oral lhrh antagonists that are out there and so they're pill so their halflife is much shorter and they have been shown to effectively suppress testosterone to the same levels as the lhrh um Agonist but their halflife is so short that people can have a rapid testosterone recovery and they do so for people who are going to get radiation treatment who need a radiation sensitizer with ADT we will typically use an oral um an oral lhrh antagonist because it's rapid on and Rapid off”