Peter Attia· MD
which is we use this cutoff of tumor shrinkage of 30 percent in writing this book i spent a lot of time trying to get the bottom of why it is this 30 percent and i found out it goes back to a 1976 paper where this mayo clinic doctor got a bunch of marbles and he put him on a dining table and he rolled out foam rubber and he got 16 oncologists to come to his house with calipers and measure the marbles and he asked at what size difference can two doctors reliably tell the marble has gotten bigger or gotten smaller and the answer was a certain cut point and that cut point is the same cut point we use today