Paul Saladino· MD
that the antipsychotics have been documented to be mitochondrial disruptors
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
that the antipsychotics have been documented to be mitochondrial disruptors
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with the antipsychotic medications we do have evidence that the antipsychotic medications cause mitochondrial dysfunction directly that that we have animal models of that and we've seen hints of it in human data
one of the main side effects unfortunately of antipsychotic treatment schizophrenia is metabolic dysfunction because many of those medications are mitochondrial poisons