There are sex differences in the rate at which drugs are excreted in humans, which should inform drug dose recommendations.

“Rich when you talk about the difference in the pharmacokinetics between male and female mice we can only extrapolate and say that our you know cytochrome p450 system as humans must have sex differences oh yeah that's well documented absolutely but what I can't tell you for the life of me rich is one drug that I'm aware of that we really differentially dose in males and females Beyond a weight difference in other words we don't seem to take into account that difference when we give a person an antibiotic or a Statin or a chemotherapy they're all based on either weight or nothing at all”