Increasing pro-convertase activity may rectify some Prader-Willi phenotypes.

“and it's relevant in the question of insulin because insulin is processed by Pro convertase so some of the s where the C peptide gets cleaved on a pre hormone that's correct so some of the hyperinsulinemia of the Parader Willi might be pro insulin and insulin Pro insulin has biological activity but much lower than native insulin and so if this turns out to be the case then it might be possible to rectify some of the product Willey phenotypes by being able to increase the activity of protein birthdays one pharmacologically or by other means”