Targeting PSMA with CAR T-cells led to patient deaths because the antigen was also present on normal cells. — Whalespan
Targeting PSMA with CAR T-cells led to patient deaths because the antigen was also present on normal cells.
⚠ High risk
We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
✕NOTSUPPORTED
⚠
High-risk intervention — consult a physician before acting.Drug-drug interactions, dose-dependence, and screening contraindications apply.
“and even very recently last several months you probably heard about this T immunity these two deaths for patients that were targeting what was thought to be a prostate specific molecule bsma but it's not it was present on normal cells and that can result in death”
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