Acetaminophen may blunt pain and temperature responses that act as governors on exercise output, potentially reducing gross mechanical work and overall capacity.

“the argument of the acetominophen literature is that the body is bumping up against a couple of set points that are acting as governors to Output one of them is pain one of them is temperature the body does not want to let you get too hot and obviously doesn't want you to tolerate too much pain acetam menen potentially blunts both of those you're arguing yeah but if part of the way it's blunting energy output or or temperature is by reducing in mechanical work gross mechanical work then you're going to probably pay a net mechanical work price yes and also let's say also capacity price you could say in in some in some regards”

“um one of the other things that um I asked him about was the use of acetam menen um again there are some data that suggest that acetam menen use uh can boost Peak um uh endurance performance by 1 to 2%”

“there are some data that suggest that acetam menen use uh can boost Peak um uh endurance performance by 1 to 2% and so I I asked Olaf you know if if um if Christian or Gustaf use aam menen themselves um during Iron Man and and he said they did not and he raised a point that I thought was interesting which is um while a Menan or Tylenol can obviously reduce the perception of pain which has been one of the arguments for why it boosts performance um it may impair um uh the athlete from giving off heat for from heat dissipation”