5-alpha reductase inhibitors artificially depress PSA levels by approximately 50%, which can mask underlying pathology. — Whalespan
5-alpha reductase inhibitors artificially depress PSA levels by approximately 50%, which can mask underlying pathology.
⚠ High risk
We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
✕NOTSUPPORTED
⚠
High-risk intervention — consult a physician before acting.Drug-drug interactions, dose-dependence, and screening contraindications apply.
“it's critical that patients are aware that your Ps artificially depressed it's I mean it's you could be masking pathology potentially is that the concern yes the PSA value will decline because PSA is a and regulated product and so when you reduce the amount of that potent Androgen you'll reduce the value of PSA it goes down by about half”
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“yes they do they become difficult to interpret and difficult to follow so if your numbers are over those than any you should just consider a kind of annual or twice in every other year kind of intensive followup it doesn't mean that you have prostate cancer but it means if you're over that median that you have a much higher risk in your future next 20 or 30 years of developing it again the issue is in young men who are on five Alpha reductors Inhibitors their PSAs are going to be very very low and you may miss a early blip”