Peter Attia· MD
so these uh these medications are uh cycle oxygenase inhibitors they reduce uh prostaglandins they red they what they do is a couple things they reduce some of the inflammation they're anti-inflammatories
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
so these uh these medications are uh cycle oxygenase inhibitors they reduce uh prostaglandins they red they what they do is a couple things they reduce some of the inflammation they're anti-inflammatories
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What they do is a couple things They reduce some of the inflammation They're anti-inflammatories So I was alluding very briefly that there are substances that can be released out in the periphery during injury that wind up that that noceptor and amplify it Prostaglandins histamines cytoines interlucans all of that this inflammatory soup that occurs after every single surgery every single injury that we experience you get this inflammatory soup and it's classly classically mediated by swelling redness temperature increases and aspirin and a COX 2 in uh COX2 inhibitor NSAIDs do a nice job in reducing that inflammation