Gabapentin and pregabalin have no lethal dose and are considered very safe, with the primary risks being sedation and falls, especially in the elderly.

“the beauty of these two drugs is uh there's no lethal dose like the only way they could kill the rats when they were studying it was to drown them in it i used to say or hit them over the head with the tablets and I would tell a patient somewhat jokingly the only way you can be hurt taking this drug is if you're struck by a truck that's carrying it um it's a little bit more nuanced than that because there are side effects yep you can fall asleep driving i tell people don't operate heavy machinery don't go you know doom buggy riding don't blah blah blah um there is in elderly patients in particular uh I warn them about falls because you can get a little unstable”